全國(guó)服務(wù)咨詢(xún)熱線(xiàn)：
                
                15000105423
                
            
                
        
                
    
                
    
                
        
    
                
    

                






                
	
                

                








                
    
                
        
                
            
                Products產(chǎn)品中心
                
            
                首頁(yè) > 產(chǎn)品中心 > 生化試劑 > 其它生化試劑 > abs42024900百日咳毒素PTX,Pertussis Toxin
                
        
                
        
    
                
    
    
                
        
        
                 
            
                
        
                
                                
                    
                
                        
                        
                
                        
                        
                
                    
                
                    
                
                        
                
                            
                                          
                                 
                                  
                  • 
                                              
                            
                
                        
                
                    
                
                
                
                
                
                  
            
                
        
            
            
                
                
                百日咳毒素PTX,Pertussis Toxin
                
                
                簡(jiǎn)要描述：百日咳毒素是由細(xì)菌Bordetella pertussis產(chǎn)生的，以蛋白質(zhì)為基礎(chǔ)的AB5型外毒素。是特定靶向G蛋白抑制G蛋白及其在信號(hào)通路中的生理功能，在傳染方面發(fā)揮重要作用；還能在鼠類(lèi)動(dòng)物中刺激建立實(shí)驗(yàn)性自身免疫疾病模型。
                
                
                  
                    
                • 產(chǎn)品型號(hào)：abs42024900
                  • 
                    
                • 廠(chǎng)商性質(zhì)：生產(chǎn)廠(chǎng)家
                  • 
                    
                • 更新時(shí)間：2025-03-26
                  • 
                    
                • 訪(fǎng)  問(wèn)  量：4577
                  • 
                    
                
                
                
            
                
            
                
        
                
        
	
                
    
    
                
    	
                
        
        	   
			  
            
            
            
            
                
            	
                詳細(xì)介紹
                
                
                
                    

                
                
                	
                    
                
                        
                            
                                
                品牌absinCAS70323-44-3
                分子式-純度>99%
                分子量-貨號(hào)abs42024900
                規(guī)格50ug供貨周期現(xiàn)貨
                主要用途特定靶向G蛋白抑制G蛋白及其在信號(hào)通路中的生理功能應(yīng)用領(lǐng)域醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)林牧漁
                
                            
                                        
                    
                
                
                產(chǎn)品描述
                描述
                Pertussis Toxin (islet-activating protein), a toxin originally isolated from Bordetella pertussis, has been shown to catalyze ADP-ribosylation of a protein in membrane preparation from rat C6 glioma cells. In addition, exposure of Chinese hamster ovary cells in culture to this compound has resulted in a clustered growth pattern response. Other experiments have shown Pertussis Toxin to block the ability of inhibitory hormones to reduce adenylate cyclase activity and enhance the ability of stimulatory hormones to activate the enzyme. Mechanistic studies have shown this toxin to consist of subunit A (active) promoter, which disrupts transmembrane signaling by ADP-ribosylating eukaryotic G-proteins, and B (binding) oligomer which helps the toxin bind to cells in vivo.
                應(yīng)用
                A toxin that blocks reduction of adenylate cyclase activity
                純度
                >99%
                活性
                Please note that this product is not activated. If your system requires activation, see Kaslow et al.,7 for suggested conditions.
                使用方法
                CHO Cell Assay: When examined in a CHO cell assay as described by Hewlett et al.,5 the lowest concentration of toxin at which a positive response (clustered growth pattern) was obtained was 0.01 ng/ml.

                Adenylate Cyclase Assay: The adenylate cyclase activity of this lot is 0.67 picomole/min/lJg in the presence of 1 μmolar calmodulin when assayed by the method of Wolff et al. 6
                儲(chǔ)存/保存方法
                This product is provided as an aseptically packaged lyophilized powder, sealed under vacuum. Store at 4°C prior to and following reconstitution, for 6 months. DO NOT FREEZE.
                基本信息
                外觀
                Lyophilized solid
                可溶性/溶解性
                Soluble in water (Miscible). Reconstitute with sterile purified water or the sterile buffer of your choice. The resulting suspension should be made uniform by gentle mixing prior to use. Do not sterile filter, as this will result in loss of material. For long term storage, reconstitute in a high ionic strength buffer, such as sterile 0.1 M sodium phosphate, pH 7.0, 0.5 M NaCI. Handle the product gently; do not vortex.
                參考文獻(xiàn)
                參考文獻(xiàn)
                1. Bradford, M.M. (1976) Anal. Biochem. 72, 248-254.
                2. Tamura, M., Nogomori, K., Murai, S., Yajima, M., Ito, K" Katada, T., Ui, M. and Ishi, S. (1982) Biochem. 21,5516-5522.
                3. Wyckoff, M., Rodbard, O. And Chramback, A. (1977) Anal. Biochem.78, 459-482.
                4. Laemmli, U.K. (1970) Nature 227, 680-685.
                5. Hewlett, E.L., Sauer, K.T., Myers, G.A., Cowell, J.L. and Guerrant, R.L. (1983) Infect. Immun. 40, 1198-1203.
                6. Wolff, J., Cook, G.H., Goldhammer, A.R. and Berkowitz, S.A. (1980) PNAS 77, 3841-3844.
                7. Kaslow, H.R., Lim, L.-K., Moss, J. and Lesikar, D.O. (1987) Biochem. 26, 123-127.
                
                
                
                
                
                產(chǎn)品咨詢(xún)
                
                
                
                     



                

                
	
                留言框  
                
	
                  
		
                • 
			
                  產(chǎn)品：
                  
			
                  
		
                  • 
		
                • 
			
                  您的單位：
                  
			
                  
		
                  • 
		
                • 
			
                  您的姓名：
                  
			
                  
		
                  • 
		
                • 
			
                  聯(lián)系電話(huà)：
                  
			
                  
		
                  • 
		
                • 
			
                  常用郵箱：
                  
			
                  
		
                  • 
        
                • 
			
                  省份：
                  
			
                  
		
                  • 
		
                • 
			
                  詳細(xì)地址：
                  
			
                  
		
                  • 
		
        
                • 
			
                  補(bǔ)充說(shuō)明：
                  
			
                  
		
                  • 
		
                • 
			
                  驗(yàn)證碼：
                  
			
                  
            	
                  
                    
                    
                
                  
                請(qǐng)輸入計(jì)算結(jié)果（填寫(xiě)阿拉伯?dāng)?shù)字），如：三加四=7
            
                  
		
                  • 
		
                • 
			
                  
			
                  
		
                  • 
	
                	
    

                

                

                
                
        
                
                
                
                
            
                
            
            
        
                
    
                


                




                
    
                
        
                
            
                
                
                
                    
                愛(ài)必信（上海）生物科技有限公司
                
                    
                地址：上海市浦東新區(qū)新浩路58號(hào)申江科創(chuàng)園18棟
                
                    
                郵箱：chenjw@absin.cn
                
                    
                傳真：
                
                
                
                
                
                
                    
                關(guān)注我們
                
                    
                歡迎您關(guān)注我們的微信公眾號(hào)了解更多信息：
                
                    
                
                        
                
                        
                歡迎您關(guān)注我們的微信公眾號(hào)
                了解更多信息
                
                    
                
                
                
            
                
        
                
       
        
                
            
                
                
            
                
        
                
    
                

                



                 
     

                





 
  




主站蜘蛛池模板：
亚洲AV日韩AV永久无码色欲|
国产v亚洲v天堂a无码|
一个人的突击队3电影在线观看|
欧美三级在线免费观看|
免费欧洲毛片A级视频无风险|
成人看片黄在线观看|
夜来香免费观看视频在线|
久久久99精品成人片|
欧美双茎同入视频在线观看
|
91国在线视频|
少妇人妻av无码专区|
久久亚洲国产精品成人AV秋霞|
欧美另类videovideosex|
人妻中文字幕乱人伦在线|
蜜桃臀无码内射一区二区三区|
国产精品久久久久久久|
99精品视频在线观看免费|
成年大片免费视频|
久久精品国产大片免费观看|
欧美精品中文字幕亚洲专区|
动漫美女被到爽流触手|
达达兔午夜起神影院在线观看麻烦
|
中文字幕乱码人妻综合二区三区
|
蝌蚪久热精品视频在线观看|
国产精品一区视频|
999这里只有精品|
女人腿张开让男人桶爽|
中文在线最新版天堂|
日本高清免费一本视频在线观看|
亚洲人成无码网站久久99热国产|
激情久久av一区av二区av三区|
午夜精品一区二区三区在线观看|
裴远之的原型人物是谁
|
欧美日韩高清完整版在线观看免费|
公天天吃我奶躁我的在线观看|
色综合67194|
孕妇被迫张开腿虐孕|
国产乱子伦农村叉叉叉|
你懂的国产视频|
在线a亚洲视频播放在线观看
|
国产精品久久久久久麻豆一区
|