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                首頁(yè) > 產(chǎn)品中心 > 細(xì)胞生物學(xué) > 重組蛋白 > abs04199SCF/c-Kit Ligand(10ug)

                SCF/c-Kit Ligand(10ug)

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                • 產(chǎn)品型號(hào):abs04199
                • 廠(chǎng)商性質(zhì):生產(chǎn)廠(chǎng)家
                • 更新時(shí)間:2025-06-07
                • 訪(fǎng)  問(wèn)  量:1791

                詳細(xì)介紹

                品牌absin貨號(hào)abs04199
                規(guī)格10ug供貨周期一周
                概述
                描述Recombinant Mouse Stem Cell Factor is produced by our E.coli expression system and the target gene encoding Lys26-Ala189 is expressed.
                別名Kit ligand,Hematopoietic growth factor KL,Mast cell growth factor,MGF,Steel factor,Stem cell factor,SCF
                形態(tài)Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
                來(lái)源E.coli
                氨基酸序列MKEICGNPVTDNVKDITKLVANLPNDYMITLNYVAGMDVLPSHCWLRDMVIQLSLSLTTLLDKFS NISEGLSNYSIIDKLGKIVDDLVLCMEENAPKNIKESPKRPETRSFTPEEFFSIFNRSIDAFKDF MVASDTSDCVLSSTLGPEKDSRVSVTKPFMLPPVA
                內(nèi)毒素水平Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
                Accession #P20826
                性能
                背景Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. It also promotes phosphorylation of PIK3R1, which is the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5.
                溶解方法Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
                保存方法Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
                純度Greater than 95% as determined by reducing SDS-PAGE.

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